The ACCLAIM Trial Defines a New Standard for Liver Ablation Verification

The ACCLAIM trial marks a turning point for ablation verification software.

The recent publication of the ACCLAIM study protocol in Trials confirms that software-based verification of ablation margins is becoming an essential component of interventional oncology practice.

This international, multicenter trial promoted by the Society of Interventional Oncology establishes a structured protocol for real-time 3D confirmation of complete ablation with margins ≥5 mm, using CE- and FDA-cleared image-processing software, while explicitly stating that ultrasound is not permitted for margin or ablation zone assessment.

According to the authors, the study aims to demonstrate that microwave ablation of colorectal liver metastases ≤2.5 cm, combined with 3D confirmation of margins greater than 5 mm, can achieve definitive local tumor control and help define margin confirmation as a new standard of care for this procedure.

This marks a clear shift toward objective, software-driven evaluation of ablation outcomes.

As 3D margin confirmation becomes integral to clinical practice, Ablation-fit is proving to be an invaluable tool for reliable, reproducible assessment of ablation completeness.

Read the ACCLAIM study protocol here: https://lnkd.in/gqWVSX82